physics.chem-ph · 2026-09-16 · No. 115
Chemical Physics, 2026-09-16.
1 new papers in physics.chem-ph. Titles, authors,
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01 — The papers
1 entries-
01
QALPA: Property-guided diffusion modeling for efficient exploration of chemical spaces of flexible molecules
Michael Hanna, Julian Cremer, Zekiye Erarslan, Leonardo Medrano Sandonas
physics.chem-ph · cs.AI
Exploring the chemical space of flexible molecules remains challenging because the vast number of possible compounds and conformations, together with the increasing cost and limited generalization of 3D generative models for larger and more complex molecules, restrict access to unexplored chemistry. Here, we introduce QALPA ("Quantum-Aware Learning for Property-space Augmentation"), a property-guided generative framework that combines an...
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