physics.ins-det · 2026-06-16 · No. 25

Instrumentation and Detectors, 2026-06-16.

1 new papers in physics.ins-det. Titles, authors, abstracts. Links to arXiv. Want this in your inbox every morning? Subscribe →

01 — The papers

1 entries
  1. 01

    Latent space mapping of interpretable structural coordinates from stochastic single-molecule signals

    Matteo Cartiglia, Sandro Kuppel, Wouter Botermans Wannes Peeters, Natan Biesmans, Liam Vandekerckhove, Eric Beamish,...

    physics.ins-det · cs.LG · physics.bio-ph · physics.chem-ph · physics.data-an · q-bio.BM

    Nanopores are versatile single-molecular sensors, but their utility is fundamentally constrained by stochastic translocation dynamics warping any encoded information. We resolve it by shifting from time-domain analysis to a learned latent-space mapping via a contrastive encoder trained exclusively on simulated signals from a physics-informed model. This encoder maps solid-state nanopore signals of engineered DNA barcodes into an interpretable...

    arxiv.org/abs/2606.16950 · PDF

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