q-bio.QM · 2026-08-19 · No. 89

Quantitative Methods, 2026-08-19.

2 new papers in q-bio.QM. Titles, authors, abstracts. Links to arXiv. Want this in your inbox every morning? Subscribe →

01 — The papers

2 entries
  1. 01

    DMT-Dens: Density-preserving manifold visualization for biological data

    Ruizhe Wang, Yixuan Dong, Bolin Yang, Bingo Wing-Kuen Ling, Fuji Yang, Zelin Zang

    q-bio.QM · cs.AI

    Motivation: Low-dimensional embeddings are widely used to explore cell-state heterogeneity in single-cell and other high-dimensional biological data. Although many methods preserve local neighborhoods, they may distort the apparent sampling density of processed observations, altering the visual contrast between dense and sparse regions and complicating the interpretation of rare, transitional, or continuous cell-state populations. Results: We...

    arxiv.org/abs/2608.17571 · PDF

  2. 02

    Leveraging generative hallucination and biophysics-informed modeling for unified biomolecular sequence-structure co-design

    Xuefeng Liu, Mingxuan Cao, Xiao Luo, Songhao Jiang, Tobin Sosnick, Jinbo Xu, Louis Maher, Rick Stevens

    q-bio.QM · cs.AI · cs.LG · q-bio.BM

    Biomolecular design underpins applications from molecular recognition to therapeutics and synthetic biology, yet de novo interaction design remains challenging-especially for DNA/RNA, underexplored non-protein modalities with scarce, heterogeneous complex data and sharper geometric and chemical constraints. We introduce MCTH (Monte Carlo Tree Hallucination), an inference-only framework that casts all-atom sequence-structure co-design as...

    arxiv.org/abs/2608.17381 · PDF

This edition is part of The Daily Abstract — q-bio.QM archive. Subscribe to receive these in your inbox each morning, automatically translated to Spanish, with reply-to-PDF: arxivdaily.ignorelist.com.

Colophon Set in Georgia, with system sans for interface chrome and a monospaced stack for code and paper identifiers. Sole accent: amber #D99C5E. Built and served on an always-free VM. The masthead is set 14% letterspaced because newspapers do that and it works.